EPA METHOD 1633
The US EPA's provisional Method 1633 is a validated laboratory procedure designed to analyze 40 PFAS compounds spanning nine classes, encompassing linear and branched isomers. This method is applicable to various environmental matrices, such as wastewater, surface water, groundwater, soil, biosolids, sediment, landfill leachate, and fish tissue. It covers not only established PFAS classes but also includes emerging ones, incorporating all analytes found in EPA drinking water Methods 533 and 537.1. This standardized and robust method is crucial for monitoring PFAS in non-potable waters, soils, and tissues to safeguard public health.
technical data sheet
METHOD CODE
LAB-TM-081
EQUIPMENT
Ultra-Performance Liquid Chromatography /
Tandem Mass Spectrometry (UPLC-MS/MS)
Tandem Mass Spectrometry (UPLC-MS/MS)
METHOD REFERENCE
EPA Method 1633
REPORTABLE UNIT
Aqueous = ng/L // Solid = ng/g
SAMPLE SIZE REQUIREMENTS
Aqueous = 3x 500 mL // Solid = 1x 250 mL bottle 3/4-full
AVAILABLE FOR
Non-potable water / groundwater / surface water / soil
ANALYTE LIST
TARGET ANALYTES
CASRN
INTERNAL STANDARD (ISTD) ANALYTES
PFBA
375-22-4
M4-PFBA
PFPeA
2706-90-3
M5-PFPeA
PFHxA
307-24-4
M5-PFHxA
PFHpA
375-85-9
M4-PFHpA
PFOA
335-67-1
M8-PFOA
PFNA
375-95-1
M9-PFNA
PFDA
335-76-2
M6-PFDA
PFUnDA
2058-94-8
M7-PFUnDA
PFDoDA
307-55-1
M2-PFDoDA
PFTrDA
72629-94-8
M2-PFTeDA
PFTeDA
376-06-7
M8-PFOSA
PFBS
375-73-5
D3-NMeFOSAA
PFPeS
2706-91-4
D5-NEtFOSAA
PFHxS
355-46-4
M3-PFBS
PFHpS
375-92-8
M3-PFHxS
PFOS
1763-23-1
M8-PFOS
PFNS
68259-12-1
M2-4:2 FTS
PFDS
335-77-3
M2-6:2 FTS
PFDoDS
79780-39-5
M2-8:2 FTS
4:2 FTS
757124-72-4
M3-HFPO-DA
6:2 FTS
27619-97-2
D7-NMeFOSE
8:2 FTS
39108-34-4
D9-NEtFOSE
NMeFOSAA
2355-31-9
D3-NMeFOSA
NEtFOSAA
2991-50-6
D5-NEtFOSA
PFOSA
754-91-6
XXX
NMeFOSA
31506-32-8
XXX
NEtFOSA
4151-50-2
XXX
NMeFOSE
24448-09-7
XXX
NEtFOSE
1691-99-2
XXX
HFPO-DA
13252-13-6
XXX
ADONA
919005-14-4
XXX
PFMPA
377-73-1
XXX
PFMBA
863090-89-5
XXX
NFDHA
151772-58-6
XXX
9Cl-PF3ONS
756426-58-1
XXX
11Cl-PF3OUdS
763051-92-9
XXX
PFEESA
113507-82-7
XXX
3:3 FTCA
356-02-5
XXX
5:3 FTCA
914637-49-3
XXX
7:3 FTCA
812-70-4
XXX
