EPA METHOD 1633
The US EPA's provisional Method 1633 is a validated laboratory procedure designed to analyze 40 PFAS compounds spanning nine classes, encompassing linear and branched isomers. This method is applicable to various environmental matrices, such as wastewater, surface water, groundwater, soil, biosolids, sediment, landfill leachate, and fish tissue. It covers not only established PFAS classes but also includes emerging ones, incorporating all analytes found in EPA drinking water Methods 533 and 537.1. This standardized and robust method is crucial for monitoring PFAS in non-potable waters, soils, and tissues to safeguard public health.
technical data sheet
METHOD CODE
LAB-TM-081
EQUIPMENT
Ultra-Performance Liquid Chromatography /
Tandem Mass Spectrometry (UPLC-MS/MS)
Tandem Mass Spectrometry (UPLC-MS/MS)
METHOD REFERENCE
EPA Method 1633
REPORTABLE UNIT
Aqueous = ng/L // Solid = ng/g
SAMPLE SIZE REQUIREMENTS
Aqueous = 3x 500 mL // Solid = 1x 250 mL bottle 3/4-full
AVAILABLE FOR
Non-potable water / groundwater / surface water / soil
ANALYTE LIST
XXX
ISTD RELATIONSHIP
TARGET ANALYTES
CASRN
INTERNAL STANDARD (ISTD) ANALYTES
XXX
TARGETS
ISTDs
PFBA
375-22-4
M4-PFBA
XXX
PFBA
M4-PFBA
PFPeA
2706-90-3
M5-PFPeA
XXX
PFPeA
M5-PFPeA
PFHxA
307-24-4
M5-PFHxA
XXX
PFHxA
M5-PFHxA
PFHpA
375-85-9
M4-PFHpA
XXX
PFHpA
M4-PFHpA
PFOA
335-67-1
M8-PFOA
XXX
PFOA
M8-PFOA
PFNA
375-95-1
M9-PFNA
XXX
PFNA
M9-PFNA
PFDA
335-76-2
M6-PFDA
XXX
PFDA
M6-PFDA
PFUnDA
2058-94-8
M7-PFUnDA
XXX
PFUnDA
M7-PFUnDA
PFDoDA
307-55-1
M2-PFDoDA
XXX
PFDoDA
M2-PFDoDA
PFTrDA
72629-94-8
M2-PFTeDA
XXX
PFTrDA
Avg. of M2-PFTeDA & M2-PFDoDA
PFTeDA
376-06-7
M8-PFOSA
XXX
PFTeDA
M2-PFTeDA
PFBS
375-73-5
D3-NMeFOSAA
XXX
PFBS
M3-PFBS
PFPeS
2706-91-4
D5-NEtFOSAA
XXX
PFPeS
M3-PFHxS
PFHxS
355-46-4
M3-PFBS
XXX
PFHxS
M3-PFHxS
PFHpS
375-92-8
M3-PFHxS
XXX
PFHpS
M8-PFOS
PFOS
1763-23-1
M8-PFOS
XXX
PFOS
M8-PFOS
PFNS
68259-12-1
M2-4:2 FTS
XXX
PFNS
M8-PFOS
PFDS
335-77-3
M2-6:2 FTS
XXX
PFDS
M8-PFOS
PFDoDS
79780-39-5
M2-8:2 FTS
XXX
PFDoDS
M8-PFOS
4:2 FTS
757124-72-4
M3-HFPO-DA
XXX
4:2 FTS
M2-4:2 FTS
6:2 FTS
27619-97-2
D7-NMeFOSE
XXX
6:2 FTS
M2-6:2 FTS
8:2 FTS
39108-34-4
D9-NEtFOSE
XXX
8:2 FTS
M2-8:2 FTS
NMeFOSAA
2355-31-9
D3-NMeFOSA
XXX
NMeFOSAA
D3-NMeFOSAA
NEtFOSAA
2991-50-6
D5-NEtFOSA
XXX
NEtFOSAA
D5-NEtFOSAA
PFOSA
754-91-6
XXX
XXX
PFOSA
M8-PFOSA
NMeFOSA
31506-32-8
XXX
XXX
NMeFOSA
D3-NMeFOSA
NEtFOSA
4151-50-2
XXX
XXX
NEtFOSA
D3-NMeFOSA
NMeFOSE
24448-09-7
XXX
XXX
NMeFOSE
D5-NEtFOSA
NEtFOSE
1691-99-2
XXX
XXX
NEtFOSE
D7-NMeFOSE
HFPO-DA
13252-13-6
XXX
XXX
HFPO-DA
D9-NEtFOSE
ADONA
919005-14-4
XXX
XXX
ADONA
M3-HFPO-DA
PFMPA
377-73-1
XXX
XXX
PFMPA
M3-HFPO-DA
PFMBA
863090-89-5
XXX
XXX
PFMBA
M5-PFPeA
NFDHA
151772-58-6
XXX
XXX
NFDHA
M5-PFHxA
9Cl-PF3ONS
756426-58-1
XXX
XXX
9Cl-PF3ONS
M3-HFPO-DA
11Cl-PF3OUdS
763051-92-9
XXX
XXX
11Cl-PF3OUdS
M3-HFPO-DA
PFEESA
113507-82-7
XXX
XXX
PFEESA
M5-PFHxA
3:3 FTCA
356-02-5
XXX
XXX
3:3 FTCA
M5-PFPeA
5:3 FTCA
914637-49-3
XXX
XXX
5:3 FTCA
M5-PFHxA
7:3 FTCA
812-70-4
XXX
XXX
7:3 FTCA
M5-PFHxA
