EPA METHOD 8327
The dilute-and-shoot liquid chromatography/tandem mass spectrometry (LC/MS/MS) method, known as US EPA Method 8327, enables swift analysis of 24 PFAS in non-potable waters like surface water, groundwater, and wastewater. Aligned with ASTM method D7979 protocols, it employs Multiple Reaction Monitoring (MRM) for improved selectivity, and quantification is achieved through external calibration.
technical data sheet
METHOD CODE
LAB-TM-079
EQUIPMENT
Ultra-Performance Liquid Chromatography /
Tandem Mass Spectrometry (UPLC-MS/MS)
Tandem Mass Spectrometry (UPLC-MS/MS)
METHOD REFERENCE
EPA Method 8327
REPORTABLE UNIT
ng/L
SAMPLE SIZE REQUIREMENTS
3x 20 mL
AVAILABLE FOR
Non-potable water / groundwater / surface water
ANALYTE LIST
SURROGATE RELATIONSHIP
TARGET ANALYTES
CASRN
SURROGATE ANALYTES
XXX
TARGETS
SURROGATES
PFBA
375-22-4
M4-PFBA
XXX
PFBA
M4-PFBA
PFPeA
2706-90-3
M5-PFPeA
XXX
PFPeA
M5-PFPeA
PFHxA
307-24-4
M5-PFHxA
XXX
PFHxA
M5-PFHxA
PFHpA
375-85-9
M4-PFHpA
XXX
PFHpA
M4-PFHpA
PFOA
335-67-1
M8-PFOA
XXX
PFOA
M8-PFOA
PFNA
375-95-1
M9-PFNA
XXX
PFNA
M9-PFNA
PFDA
335-76-2
M6-PFDA
XXX
PFDA
M6-PFDA
PFUnDA
2058-94-8
M7-PFUnDA
XXX
PFUnDA
M7-PFUnDA
PFDoDA
307-55-1
M2-PFDoDA
XXX
PFDoDA
M2-PFDoDA
PFTrDA
72629-94-8
M2-PFTeDA
XXX
PFTrDA
M2-PFDoDA
PFTeDA
376-06-7
M8-PFOSA
XXX
PFTeDA
M2-PFTeDA
PFBS
375-73-5
D3-NMeFOSAA
XXX
PFBS
M3-PFBS
PFPeS
2706-91-4
D5-NEtFOSAA
XXX
PFPeS
M3-PFBS
PFHxS
355-46-4
M3-PFBS
XXX
PFHxS
M3-PFHxS
PFHpS
375-92-8
M3-PFHxS
XXX
PFHpS
M3-PFHxS
PFOS
1763-23-1
M8-PFOS
XXX
PFOS
M8-PFOS
PFNS
68259-12-1
M2-4:2 FTS
XXX
PFNS
M8-PFOS
PFDS
335-77-3
M2-6:2 FTS
XXX
PFDS
M8-PFOS
4:2 FTS
757124-72-4
M2-8:2 FTS
XXX
4:2 FTS
M2-4:2 FTS
6:2 FTS
27619-97-2
xxx
xxx
6:2 FTS
M2-6:2 FTS
8:2 FTS
39108-34-4
xxx
xxx
8:2 FTS
M2-8:2 FTS
NMeFOSAA
2355-31-9
xxx
xxx
NMeFOSAA
D3-NMeFOSAA
NEtFOSAA
52991-50-6
xxx
xxx
NEtFOSAA
D5-NEtFOSAA
PFOSA
754-91-6
xxx
xxx
PFOSA
M8-PFOSA
